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R Al-Hasani, JMT Wong, OS Mabrouk, JG McCall, GP Schmitz, ... (2018) In vivo detection of optically-evoked opioid peptide release. Elife

G Corder, DC Castro, MR Bruchas, G Scherrer (2018) Endogenous and exogenous opioids in pain. Annual Review of Neuroscience.

D Seo, LE Motard, MR Bruchas (2018) Contemporary strategies for dissecting the neuronal basis of neurodevelopmental disorders. Neurobiology of Learning and Memory.

L Lu, P Gutruf, L Xia, DL Bhatti, X Wang, A Vazquez-Guardado, X Ning, ... (2018) Wireless optoelectronic photometers for monitoring neuronal dynamics in the deep brain. Proc Natl Acad Sci USA.


J.G. McCall, E.R. Siuda, D.L. Bhatti, L.A. Lawson, Z.A. McElligott, G.D. Stuber, M.R. Bruchas. (2017) Locus Coeruleus to Basolateral Amygdala Noradrenergic Projections Promote Anxiety-like Behavior.  Elife.  July 14; 6 

L. Xia, S.K. Nygard, G.G. Sobczak, N.J. Hourguettes, M.R. Bruchas. (2017) Dorsal-CA1 Hippocampal Neuronal Ensembles Encode Nicotine-Reward Contextual Associations.  Cell Rep.  19(10):2143-2156

G. Shin, A.M. Gomez, R. Al-Hasani, Y.R. Jeong, J. Kim, Z. Xie, A. Banks, S.M. Lee, S.Y. Han, C.J. Yoo, J.L. Lee, S.H. Lee, J. Kurniawan, J. Tureb, Z. Guo, J. Yoon, S.I. Park, S.Y. Bang, Y. Nam, M.C. Walicki, V.K. Samineni, A.D. Mickle, K. Lee, S.Y. Heo, J.G. McCall, T. Pan, L. Wang, X. Feng, T.I. Kim, J.K. Kim, Y. Li, Y. Huang, R.W. 4th Gereau, J.S. Ha, M.R. Bruchas, J.A. Rogers. (2017) Flexible Near-Field Wireless Optoelectronics as Subdermal Implants for Broad Applications in Optogenetics.  Neuron.  8;93(3):509-521

J.G. McCall, R. Qazi, G. Shin, S. Li, M.H. Ikram, K. Jang, Y Liu, R. Al-Hasani, M.R. Bruchas, J. Jeong, J.A. Rogers. (2017) Preparation and Implementation of Optofluidic Neural Probes for in vivo Wireless Pharmacology and Optogenetics.  Nature Protocols. 12(2):219-237


S.I. Park, G. Shin, J.G McCall, R. Al-Hasani, A. Norris, L. Xia, D.S. Brenner, K.N. Noh, S.Y. Bang, D.L. Bhatti, K.I. Jang, S.K. Kang, A.D. Mickle, G. Dussor, T.J. Price, R.W. Gereau 4th, M.R. Bruchas, J.A. Rogers. (2016) Stretchable Multichannel Antennas in Soft Wireless Optoelectronic Implants for Optogenetics.  Proc Natl Acad Sci USA. 113(50):E8169-E8177

S.M. Spangler, M.R. Bruchas. (2016) Optogenetic approaches for dissecting neuromodulation and GPCR signaling in neural circuits. Curr Opin Pharmacol. 19;32:56-70

D. Seo, S. Funderburk, D. Bhatti, L. Motard, D. Newbold, K. Girven, J.G. McCall, M. Krashes, D. Sparta, M.R. Bruchas. (2016) A GABAergic Projection from the Centromedial Nuclei of the Amygdala to Ventromedical Prefrontal Cortex Modulates Reward Behavior.  J. Neuroscience. 36(42):10831-10842

S. Nygard, N. Hourgettes, W.A. Carlezon, M.R. Bruchas. (2016) Stress-induced Reinstatement of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity in the Basolateral Amygdala.  J. Neuroscience 36(38):9937-48

P. Namburi, R. Al-Hasani, G.G. Calhoon, M.R. Bruchas, K.M. Tye. (2016) Architectural Representation of Valence in the Limbic System. Neuropsychopharmacology. 41:1697-715

L. Toll, M.R. Bruchas, G. Calo', B.M. Cox, N.T. Zaveri. (2016) Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems. Pharmacological Reviews. 68:419-57

N.A. Crowley, D.W. Bloodgood, J.A. Hardaway, A.M. Kendra, J.G. McCall, R. Al-Hasani, N.M. McCall, W. Yu, Z.L. Schools, M.J. Krashes, B.B. Lowell, J.L. Whistler, M.R. Bruchas, T.L. Kash. (2016) Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit. Cell Reports. 14(12):2774-83

R.P. Gupte, S. Kadunganattil, A.J. Shepherd, R. Merrill, W. Planer, M.R. Bruchas, S. Strack, D.P. Mohapatra. (2016) Convergent Phosphomodulation of the Major Neuronal Dendritic Potassium Channel Kv4.2 by Pituitary Adenylate Cyclase-activating Polypeptide.  Neuropharmacology.  101:291-308

M.R. Bruchas, B.L. Roth. (2016) New Technologies for Elucidating Opioid Receptor Function.  Trends Pharmacol Sci. 37:279-89

E.R. Siuda, R. Al-Hasani, J.G. McCall, D.L. Bhatti, M.R. Bruchas. (2016) Chemogenetic and Optogenetic Activation of Gas Signaling in the Basolateral Amygdala Induces Acute and Social Anxiety-Like States.  Neuropsychopharmacology. 41:2011-23


S.I. Park, D.S. Brenner, G. Shin, C.D. Morgan, B.A. Copits, H.U. Chung, M.Y. Pullen, K.N. Noh, S. Davidson, S.J. Oh, J. Yoon, K.I. Jang, V.K. Samineni, M. Norman, J.G. Grajales-Reyes, S.K. Vogt, S.S. Sundaram, K.M. Wilson, J.S. Ha, R. Xu, T. Pan, T.I. Kim, Y. Huang, M.C. Montana, J.P. Golden, M.R. Bruchas, R.W. Gereau IV, J.A. Rogers. (2015) Soft, Stretchable, Fully Implantable Miniaturized Optoelectronic System for Wireless Optogenetics Nat Biotechnol.  33:1280-1286

E.R. Siuda, J.G McCall, R. Al-Hasani, G. Shin, S. Park II, M.J. Schmidt, S.L. Anderson, W.J. Planer, J.A Rogers, M.R. Bruchas. (2015) Optodynamic Simulation of β-adrenergic Receptor Signalling. Nat Commun. 6:8480 

R. Al-Hasani, J.G. McCall, G. Shin, A.M. Gomez, G.P. Schmitz, J.M. Bernardi, C.O. Pyo, S.I. Park, C.M. Marcinkiewcz, N.A. Crowley, M.J. Krashes, B.B. Lowell, T.L. Kash, J.A. Rogers, M.R. Bruchas. (2015) Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and RewardNeuron. 87:1063-1077

J.W. Jeong*, J.G. McCall*, G. Shin, Y. Zhang, R. Al-Hasani, M. Kim, S. Li. J.Y. Sim, K.I. Jang, Y. Shi, D.Y. Hong, Y. Liu, G.P. Schmitz, L. Xia, Z. He, P. Gamble, W.Z. Ray, Y. Huang, M.R. Bruchas*, J.A. Rogers*. (2015) Wireless Optofluidic Systems for Programmable In Vivo Pharmacology and OptogeneticsCell. 162:662-674 equal contribution, co-corresponding authors

J.G. McCall, R. Al-Hasani, E.R. Siuda, D.Y. Hong, A.J. Norris, C.P. Ford, M.R. Bruchas. (2015) CRH Engagement of the Locus Coeruleus Noradrenergic System Mediates Stress-Induced Anxiety. Neuron. 87:605-620

S.D. Chang, S.W. Mascarella, S.M. Spangler, V.V. Gurevich, H.A. Navarro, F.I. Carroll. M.R. Bruchas. (2015) Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid ReceptorMolecular Pharmacology. 88:502-511

E.R. Siuda, B. Copits, M.Schmidt, M. Baird, R. Al-Hasani, W. Planer, S. Funderburk, J.G. McCall, R.W. Gereau IV, M.R. Bruchas (2015). Spatiotemporal Control of Opioid Signaling and Behavior.  Neuron. 86:923-935


G.S. Portugal*R. Al-Hasani*A FakiraJ.Gonzalez-RomeroZ. MelyanJ.G. McCallM.R. Bruchas*, and J.A. Morón Concepcion*(2014) Hippocampal long-term potentiation (LTP) is disrupted during expression and extinction but is restored following reinstatement of morphine place preferenceJ. Neurosci. 34:527-38.  * equal contribution, co-corresponding authors

S.D. Chang and M.R. Bruchas. (2014) Functional Selectivity at GPCRs:  New Opportunities in Psychiatric Drug Discovery.  Neuropsychopharmacology.


J.G. McCall, T.-I. Kim, G. Shin, X. Huang, Y.H. Jung, F. Omenetto, M.R. Bruchas*, J.R. Rogers* (2013). Fabrication of flexible, multimodal light emitting devices for wireless optogenetics. Nature Protocols, 12:2413-28.  * equal contribution, co-corresponding authors

R. Al-Hasani, A.M. Foshage, J.G. McCall, M.R. Bruchas (2013) Locus Ceoruleus Kappa Opioid Receptors Modulate Reinstatement of Cocaine Place Preference through a Noradrenergic MechanismNeuropsychopharmacology,8:2484-97.

R. Al-Hasani, J.G. McCall, M.R. Bruchas (2013) Exposure to chronic mild stress prevents reinstatement of kappa-opioid mediated cocaine and nicotine place preference.  Frontiers in Pharmacology, 4:96.

T.-I. Kim*, J.G. McCall*, Y.H. Jung, X. Huang, E.R. Siuda, Y. Li, J. Song, Y.M. Song, H.A. Pao, R.-H Kim, C. Lu, S.D. Lee, I.S. Song, G.C. Shin, R. Al-Hasani, S. Kim, M.P. Tan, Y. Huang, F. Omenetto, J.A. Rogers* and M.R. Bruchas*  (2013)   Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics.  Science, 340:211-216.


Zhang NR, Planer W, Siuda ER, Zhao HC, Stickler L, Baird MA, Cao YQ and Bruchas MR  (2012). Serine 363 is Required for NOPR Desensitization, Internalization, and Arrestin SignalingJ. Bio Chem.  50:42019-42030. 

Crock LW, Kolber BJ, Morgan CD, Sadler KE, Vogt SK, Bruchas MR, and Robert Gereau IV (2012) Central amygdala mGluR5 in the modulation of visceral pain.  J Neurosci. 32:14217-26.

Smith J., Schindler A.G., Gustin R., Bruchas M.R., Chavkin C. (2012) Stress-induced activation of the dynorphin/kappa-opioid receptor system in the amygdala potentiates nicotine conditioned place preference.  J. Neurosci, 32:1488-95.


Al-Hasani R. and Bruchas M.R. (2011) Molecular Mechanisms of Opioid Receptor-dependent Signaling and BehaviorAnesthesiology. 115:1363-81.

Bruchas M.R. , Schindler A.G., Shankar H., Messinger D.I., Miyatake M., Land B.B., Lemos J.C., Hagan C., Neumaier J., Quintana A., Palmiter R., Chavkin C. (2011). p38alpha MAPK deletion in serotonergic neurons produces stress-resilience in models of depression and addiction.  Neuron, 71, 498-511.


For more visit: Bruchas MR on PubMed | Link